The Role of Cellulose in the Formulation of Interconnected Macro and Micoporous Biocompatible Hydroxyapatite Scaffolds

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J. Anita Lett, M. Sundareswari, K. Ravichandran, Amirdha Sher Gill, J. Joyce Prabhkar (2017). The Role of Cellulose in the Formulation of Interconnected Macro and Micoporous Biocompatible Hydroxyapatite ScaffoldsMechanics, Materials Science & Engineering, Vol 9. doi:10.2412/mmse.62.43.650

Authors: J. Anita Lett, M. Sundareswari, K. Ravichandran, Amirdha Sher Gill, J. Joyce Prabhkar

ABSTRACT. In bone tissue engineering, ceramics are widely used as implant material to enhance bone growth formation or as drug release vehicle. In the existing work porous Hydroxyapatite scaffolds were prepared by polymeric replication method using Cellulose as a binding agent. The influence of binder on various sintering temperature were evaluated. The Hydroxyapatite scaffold sintered at 1150°C was characterized for phase purity, structural analysis and porosity measurements. Hence, it is possible to produce Hydroxyapatite scaffolds with highly inter connecting macro and micro pores with an apparent density of 0.944g/cm3 corresponding to 75% porosity.

Keywords: bone tissue engineering, pure hydroxyapatite scaffolds, cellulose, porosity

DOI 10.2412/mmse.62.43.650

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